What has led to the development of methicillin resistant Staphylococcus aureus MRSA )? Quizlet?

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What causes methicillin

MRSA is usually spread in the community by contact with infected people or things that are carrying the bacteria. This includes through contact with a contaminated wound or by sharing personal items, such as towels or razors, that have touched infected skin.

How did methicillin

Gram-positive bacteria acquire resistance to beta-lactam antibiotics through the production of a protein called PBP2a, which is able to avoid the inhibitory effects of the antibiotics. This is the mechanism by which MRSA is able to persist despite treatment with multiple beta-lactam antibiotics.

How did Staphylococcus aureus evolve into MRSA Methicillin

Five major lineages of methicillin-resistant Staphylococcus aureus [MRSA] have evolved since the introduction of methicillin for the treatment of infections caused by penicillin-resistant S. aureus in 1959. The clones of these lineages are responsible for the vast majority of hospital-acquired MRSA disease globally.

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